Objective: Cardiac arrest is one of the most critical emergencies encountered in the emergency department, requiring immediate intervention due to its high mortality and morbidity. Early prediction of return of spontaneous circulation (ROSC) is crucial for refining resuscitation strategies and improving outcomes. The current study aims to assess the predictive value of hematological parameters and blood gas variables in determining ROSC following cardiac arrest.
Materials and Methods: This study analyzed patients with cardiac arrest or who experienced cardiac arrest during their follow-up in the Emergency Department of Etlik City Hospital between May 1, 2024, and November 30, 2024. Demographic data, as well as initial laboratory values including white blood cell count, lymphocyte, monocyte, neutrophil, platelet count and blood gas parameters, were recorded and analyzed.
Results: Of the 1,015 patients initially screened, 997 patients fulfilled the inclusion criteria and were analyzed in the final dataset. The median lactate level was significantly lower in the ROSC group at 2.64 mmol/L, compared to 4.56 mmol/L in the non-ROSC group (p<0.001). Similarly, the median PLR was notably higher in the ROSC group at 206.7, whereas it was 30.62 in the non-ROSC group (p<0.001). PLR demonstrated very good discriminative ability for ROSC prediction (AUC: 0.823).
Conclusion: PLR, a readily accessible and cost-effective parameter, demonstrated a strong predictive value for ROSC in patients with cardiac arrest. Additional prospective studies are required to verify these results in broader patient groups.